胆总管结石再形成原因的临床观察

Causes of choledocholith re-forming

目的观察胆囊切除、十二指肠乳头肌切开等因素与胆总管结石再形成的关系。方法回顾性分析郑州大学第一附属医院2005年1月至2010年12月再发胆管结石246例患者的临床资料，分析胆囊切除、十二指肠乳头肌切开（EST）范围与胆总管结石再形成的关系。结果胆囊切除术后胆总管结石再形成的时间间隔较术前缩短，EST术大开口较小开口，胆总管结石再形成的时间间隔缩短，胆囊切除并行EST术后胆总管结石再次形成胆总管结石的几率升高。结论胆囊切除、十二指肠乳头肌切开可能是胆总管结石再形成的高危因素。

Objective To observe the relationship of the fators （cholecystectomy, endoscopic sphincterotomy） and the recurrence of choledocholith. Methods Retrospectivly analyzed the clinical data of 246 patients who attacked choledocholith from January 2005 to December 2010, and analyzed the relation.between the reformulation of choledocholith with cholecystectomy, endoscopic sphincterotomy （EST）. Results The time intervals of choledocholith reforming reduced after cholecystectomy. The time intervals of choledocholith reforming that EST with large incisions was shorten compared with smaller incisions. The rate of recurrence of choledocholith that EST and eholecystectomy increased. Conclusions Cholecystectomy, endoscopic sphincterotomy （EST） are independent factors in the reformulation of choledocholith.