基于医院监测的围生儿先天性心脏病流行病学调查分析

Epidemiological analysis of perinatal congenital heart disease based on hospital monitoring

目的了解河南省围生儿先天性心脏病的发生现状及动态发展趋势，掌握其流行病学特征，选择合适的诊断方法。方法按照全国以医院为基础的出生缺陷监测方案，利用本省75所监测医院上报的2007年至2010年资料进行回顾性分析。结果4年先天性心脏病发生率呈波动性，最低是2007年的4．45／万，最高是2010年的5．56／万，平均先天性心脏病发生率为4．97／万。2007年居出生缺陷的第6位，近3年来一直处于第5位；4年报告先天性心脏病375例，男149例，女225例，性别不明1例；城镇217例，乡村158例；B超诊断303例，占80．8％；单发285例，合并其他畸形90例。结论提高先天性心脏病B超产前诊断水平，关注重点人群，切实降低先天性心脏病儿的发生率。

Objective To understand occurrence and development trends of the provincial perinatal congenital heart disease, grasp its cpidemiological characteristics, selection of appropriate diagnostic method. Methods According to the national hospital based birth defects surveillance programs, with the province in 75 hospitals which had reported from 2007 to 2010 year were retrospectively analyzed. Results Incidence rate of four year congenital heart disease fluctuated, the minimum was 4. 45 per ten thousand in 2007, the maximum was 5.56 per ten thousand in 2010, average congenital heart disease incidence rate was 4. 97 / 10000. In 2007 sixth birth defects, nearly 3 years had been in fifth; 4 years re： port of 375 cases with congenital heart disease, male 149 cases, female 225 cases, of unknown gender in 1 case; 217 cases of villages 158 cases of; By ultrasound diagnosis in 303 cases, the proportion was 80. 8% ; one in 285 cases, combined with other malformation in 90 cases. Conclusions To improve the prenatal diagnosis of congenital heart disease with B ultrasound, pay attention on focus groups, can reduce the incidence of congenital heart disease.