ER、PR及同源框基因11在种植窗期子宫内膜组织中的表达及意义
被引量:4
摘要
子宫内膜容受性下降是造成胚胎种植率低、复发性早期流产的重要原因。ER、PR及同源框基因(HOXA)11的表达水平异常,均可导致子宫内膜环境变化,降低子宫内膜的容受性。本研究通过检测行体外受精一胚胎移植(IVF-ET)患者月经周期种植窗期血清雌二醇、孕酮的水平,ER、
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2012年第8期629-631,共3页
Chinese Journal of Obstetrics and Gynecology
参考文献6
-
1徐苗厚,张振国,江森,许燕雪.黄体功能缺陷与子宫内膜效应不良患者的内分泌特征[J].中华妇产科杂志,1997,32(3):141-144. 被引量:20
-
2Gendron RL, Paradis H, Hsieh-Li HM, et al. Abnormal uterine stromal and glandular function associated with maternal reproductive defects in Hoxa-11 null mice. Biol Reprod, 1997,56: 1097-1105.
-
3Wang LF, Luo HZ, Zhu ZM, et al. Expression of HOXA-11gene in human endomtrium. Am J Obstet Gynecol, 2004,191:767- 772.
-
4霍立军,杨增明.孕酮调节的胚胎着床相关分子及其作用[J].中华妇产科杂志,2002,37(8):505-507. 被引量:14
-
5Molina R, Castilla JA, Vergara F, et al. Luteal cytoplasmic estradiol and progesterone receptors in human endometrium: in vitro fertilization and normal cycles. Fertil Steril, 1989,51:976- 979.
-
6Taylor HS, Lgarashi P, Olive DL, et al. Sex steroid mediate HOXA-11 expression in the human peri-implantation endometrium. J Clin Endocrinol Metab, 1999, 84 : 1129-1135.
二级参考文献13
-
1徐苗厚,现代妇产科进展,1994年,3卷,176页
-
2丁菊红,中华妇产科杂志,1990年,25卷,43页
-
3凌玲,中华妇产科杂志,1989年,24卷,198页
-
4Giudice LC.Potential biochemical markers of uterine receptivity[].Human Reproduction.1999
-
5Hambartsoumian E,Taupin JL,Moreau JF,et al.In-vivo administration of progesterone inhibits the secretion of endometrial leukaemia inhibitory factor in vitro[].Molecular Human Reproduction.1998
-
6Lim H,Ma L,Ma WG,et al.Hoxa-10 regulates uterine stromal cell responsiveness to progesterone during implantation and decidualization in the mouse[].Journal of Molecular Endocrinology.1999
-
7Grummer R,Winterhager E.Regulation of gap junction connexins in the endometrium during early pregnancy[].Cell and Tissue Research.1998
-
8Yue ZP,Yang ZM,Wei P,et al.Leukemia inhibitory factor, leukemia inhibitory factor receptor, and glycoprotein 130 in rhesus monkey uterus during menstrual cycle and early pregnancy[].Biology of Reproduction.2000
-
9Sharkey AM,King A,Clark DE,et al.Localization of leukemia inhibitory factor and its receptor in human placenta throughout pregnancy[].Biology of Reproduction.1999
-
10Zhu LJ,Cullinan-Bove K,Polihronis M,et al.Calcitonin is a progesterone-regulated marker that forecasts the receptive state of endometrium during implantation[].The Journal of Endocrinology.1998
共引文献30
-
1刘艳娟,黄光英,杨明炜,陆付耳.补肾益气中药对小鼠围着床期子宫内膜形态结构及PR表达的影响[J].浙江中医药大学学报,2007,31(6):690-692. 被引量:6
-
2常瑞萍,赵可宁.黄体功能不健的不孕症中医临床研究[J].辽宁中医药大学学报,2009,11(4):84-86. 被引量:4
-
3糜叶俊,王玉蓬,糜黎娜,赵淑敏.38例不孕症黄体中期子宫内膜分泌反应观察及促黄体成熟药物应用疗效探讨[J].青岛医药卫生,2001,33(1):18-20.
-
4刘艳娟,黄光英,杨明炜,龚萍,张明敏,陆付耳.Effects of Jiantaiye (健胎液) on Estrogen Receptor and mRNA Expressions in Uterus of Mice with Embryo Implantation Dysfunction[J].Chinese Journal of Integrated Traditional and Western Medicine,2005,11(1):41-44. 被引量:2
-
5刘艳娟,黄光英,杨明炜,龚萍,陆付耳.健胎液对小鼠着床期子宫内膜孕激素受体及mRNA的影响[J].中医杂志,2005,46(4):300-302. 被引量:2
-
6刘艳娟,黄光英,杨明炜,陆付耳.健胎液对模型小鼠着床期子宫内膜容受性的影响[J].安徽中医学院学报,2006,25(5):28-32. 被引量:17
-
7董方莉,谭丽,郑英.植入窗期血清孕激素水平及子宫内膜白血病抑制因子表达对体外受精-胚胎移植结局的预测价值[J].生殖医学杂志,2007,16(1):20-23. 被引量:14
-
8施晓波,张晶,符书馨.多囊卵巢综合征患者早期流产与子宫内膜雌孕激素受体的关系[J].中南大学学报(医学版),2008,33(6):518-522. 被引量:22
-
9郭品端,王小红.阴道B超评价克罗米芬治疗周期性子宫内膜反应与妊娠的关系[J].中国医学影像学杂志,1998,6(1):46-47. 被引量:1
-
10丁彩飞,郑若姮,张永华,杨欣,孙中明,杜静.助孕汤对育龄期妇女子宫内膜容受性的影响[J].中医杂志,2009,50(4):317-320. 被引量:15
同被引文献27
-
1王瑶,冯云,牛志宏,黄晓燕,张爱军.子宫内膜轻创对着床相关因子及IVF妊娠结局影响的研究[J].生殖与避孕,2007,27(7):454-462. 被引量:85
-
2de Mouzon J, Goossens V, Bhattacharya S, et al. Assisted re-productive technology in Europe, 2006 : results generated fromEuropean registers by ESHRE[J]. Hum Reprod, 2010,25(8): 1851 -1862.
-
3Hanna A,Ariel R. Endometrial receptivity marks,the journeyto successful embryo implantation[J]. Hum Reprod Update,2006,12 ( 6 ): 731 -746.
-
4Sakumoto T, Inafuku K, Miyara M, et al. Hysteroscopic as-sessment of midsecretory - phase endometrium, with specialreference to the luteal phase defect[ J]. Horm Res, 1992,37 (Suppl 1) : 48 -52.
-
5Tawfeek MA, Eid MA,Hasan AM,et al. Assessment of leu-kemia inhibitory factor and glycoprotein 130 expression in en-dometrium and uterine flushing : a possible diagnostic tool forimpaired fertility[J]. BMC Women's Health, 2012,12(1): 10.
-
6Tsai HD,Chang CC, Hsieh YY,et al. Leukemia inhibitoryfactor concentration in different endometrial locations betweenfertile and infertile women throughout different menstrual pha-ses [J] . J Assist Reprod Genet, 2000, 17 (8) ; 415 -418.
-
7Raziel A, Schachter M, Strassburger D, et al. Favorable in-fluence of local injury to the endometrium in intracytoplasmicsperm injection patients with high order implantation failure[J]. Fertil Steril, 2007,87 (1) : 198-201.
-
8黄晓东,陈文萍.子宫内膜修整治疗不孕不育患者临床分析[J].罕少疾病杂志,2008,15(1):34-35. 被引量:4
-
9李涛,范妤,刘芳.免疫组织化学图像光密度分析的标准化方法[J].解剖学杂志,2008,31(5):727-728. 被引量:30
-
10李素春,冯苗,聂琼英,潘萍,吴穗姝,伍洁华,程少霞,康举龄,郭祖文.种植窗口期宫腔镜检查对原因不明不孕症患者子宫内膜容受性及妊娠结局的预测价值[J].中华妇产科杂志,2010,45(3):184-190. 被引量:11
引证文献4
-
1彭丹,覃桂荣,李柳铭,蒋晓莉.宫腔镜子宫内膜微创术对子宫内膜容受性生化指标的影响[J].中国妇幼保健,2014,29(32):5321-5325. 被引量:11
-
2刘燕,宋燕,刘娟,邱勇华,李丽.子宫内膜搔刮术对改善子宫内膜容受性的研究[J].当代医学,2015,21(36):16-17. 被引量:4
-
3林静,李廉.宫腔镜下子宫内膜轻创术对子宫内膜容受性相关指标的影响[J].中国妇幼保健,2017,32(23):6018-6020. 被引量:9
-
4张传厚,李莉,李芳芳.宫腔镜手术对子宫内膜容受性相关指标的影响[J].滨州医学院学报,2020,43(4):278-280. 被引量:1
二级引证文献24
-
1刘燕,宋燕,刘娟,邱勇华,李丽.子宫内膜搔刮术对改善子宫内膜容受性的研究[J].当代医学,2015,21(36):16-17. 被引量:4
-
2王丽琼.不明原因不孕不育患者治疗中采用宫腔镜下子宫内膜搔刮术联合宫腔使用几丁糖的临床疗效及安全性分析[J].兵团医学,2018(3):27-29. 被引量:2
-
3莫秋,孙晓玲,王冬纳,胜稳静,余艳萍,吴又明.归肾丸对PCOS不孕症患者着床窗期子宫内膜容受性的影响[J].中国医学创新,2016,13(32):70-73. 被引量:13
-
4李翠霞.宫腔镜子宫内膜微创术对子宫内膜容受性影响的研究[J].中国农村卫生,2016,8(10X):95-95. 被引量:1
-
5林静,李廉.宫腔镜下子宫内膜轻创术对子宫内膜容受性相关指标的影响[J].中国妇幼保健,2017,32(23):6018-6020. 被引量:9
-
6宋俏蔚,赵珊琼.滋肾凉血调周法对内异症性不孕症患者子宫内膜ER、PR、VEGF表达的影响及其与子宫内膜容受性的关系[J].中华全科医学,2018,16(1):122-125. 被引量:10
-
7陈君玉,伍亚玲,何金华.子宫内膜微创预处理对PCOS患者子宫内膜形态、厚度及临床妊娠率的影响[J].中国妇幼保健,2018,33(11):2544-2546. 被引量:2
-
8王天霞.子宫内膜微创术对不孕患者生殖内分泌、子宫内膜容受性的影响[J].中国妇幼保健,2018,33(11):2549-2552. 被引量:6
-
9雷敏,黄开淑.微刺激术对子宫内膜容受性影响的新进展[J].中国医师杂志,2018,20(9):1438-1440. 被引量:3
-
10王聪,刘敏利,黄绘.子宫内膜轻创术对体外受精胚胎移植术结局的影响[J].系统医学,2018,3(21):124-126.
-
1刘程,朱颍,刘颖,曹云霞.HOXA10基因与子宫内膜容受性的研究进展[J].中华临床医师杂志(电子版),2011,5(23):7073-7075. 被引量:8
-
2王华丽,李豫峰.超促排卵(COH)中不同E_2水平对IVF-ET术后黄体酮支持方案的选择[J].中国优生与遗传杂志,2008,16(12):129-130. 被引量:4
-
3闫瑛,陶书超,李正国,刘锋.绝经后妇女血清雌二醇浓度与血脂水平的关系[J].中国卫生产业,2011,8(07X):75-75. 被引量:1
-
4张馨月,张丽娜,刘睿智,张利群.人绒毛膜促性腺激素注射日孕酮水平与体外受精-胚胎移植结局的相关性[J].中国妇幼保健,2013,28(26):4339-4340. 被引量:1
-
5李刚.子宫腔哪个部位更适合胚胎移植[J].国外医学(计划生育分册),2005,24(6):330-331.
-
6李权,谭晓珊,陈家仙,王丽,李艳.A、C型子宫内膜种植窗期形态学特征[J].中国妇幼保健,2009,24(1):84-86. 被引量:11
-
7陈倩,王佩飞,梁玉杰,黄丽娜.子宫腺肌病患病影响因素的logistic回归分析[J].浙江医学,2015,37(5):389-392. 被引量:4
-
8吕忠梅,孙炜,倪俏.轻刮术改善内膜容受性有效性的Meta分析[J].中国妇幼健康研究,2015,26(5):944-948. 被引量:3
-
9罗罗,安福生.来自“好孕博士”的建议:大龄妈妈如何备孕二胎[J].健康与营养,2016,0(10):28-29.
-
10张惠云,邱美英,刘伟国.围绝经期女性血清雌二醇及卵泡刺激素变化规律及其与腰椎、髋部和股骨颈骨密度的关系[J].中国妇幼保健,2016,31(12):2503-2504. 被引量:9