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Confounding factors affect the pathophysiology of eosinophilic esophagitis 被引量:6

Confounding factors affect the pathophysiology of eosinophilic esophagitis
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摘要 Eosinophilic esophagitis is a newly diagnosed esophageal disease in adult and children. The clinical and pathological characteristics of this disease have been established and were recently summarized in the expert clinical guideline published in 2011. In spite of the wide knowledge accumulated on this disease, there are many areas where scientific data are missing, especially in regard to the disease's pathophysiology. Recent publications have suggested that other confounding factors modify the disease and may affect its clinicalphenotypic presentation. Those factors may include place of living, air pollution, race, genetic factors and other. In the present report we discussed and review those confounding factors, the new developments, and what direction we should go to further advance our knowledge of this disease. Eosinophilic esophagitis is a newly diagnosed esophageal disease in adult and children. The clinical and pathological characteristics of this disease have been established and were recently summarized in the expert clinical guideline published in 2011. In spite of the wide knowledge accumulated on this disease, there are many areas where scientific data are missing, especially in regard to the disease's pathophysiology. Recent publications have suggested that other confounding factors modify the disease and may affect its clinicalphenotypic presentation. Those factors may include place of living, air pollution, race, genetic factors and other. In the present report we discussed and review those confounding factors, the new developments, and what direction we should go to further advance our knowledge of this disease.
作者 Yoram Elitsur
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第33期4466-4469,共4页 世界胃肠病学杂志(英文版)
关键词 嗜酸性粒细胞 病理特点 生理机制 食管 混杂 知识积累 科学数据 病理生理 Eosinophilic esophagitis Confounding factors Race Gender Environment
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