临床药师参与1例药品不良事件的判断与救治体会

Experience of Clinical Pharmacists Participating in Judgment and Treatment of a Case of Adverse Drug Events

目的:探讨临床药师参与药品不良事件判断与救治的方法。方法:对临床药师参与药品不良事件判断与救治的1例苹果酸氯波必利片引起的药源性扭转痉挛或肌张力障碍的典型案例进行分析。结果:给予抗胆碱氢溴酸山莨菪碱(654-2),并立即上报药品不良反应。结论:临床药师需要在实践中强化药品不良事件判断与救治的临床思维能力,协助医师为患者提供高质量的药学服务。最好利用循证医学的方法,将临床证据、熟练的临床经验和患者的具体情况这三大要素紧密结合,寻找和收集最佳临床证据,重视确凿的临床证据,进行荟萃分析,并根据这些证据解决临床实际问题。

OBJECTIVE： To explore the approach and methods for clinical pharmacists to take part in judgment and treatment of adverse drug events. METHODS： One typical cases of Clebopride malate tablets induced torsion spasm or dysmyotonia in which the clinical pharmacists had participated were reported and analyzed. RESULTS： The patient was given anticholinergic anisodamine （654-2）, and adverse drug reactions were reported. CONCLUSION： Clinical pharmacists should strengthen their clinical thinking ability in the practice of adverse drug events diagnosis and treatment so as to be able to assist the physicians in providing high-quali- ty pharmaceutical care. By using evidence-based medicine, clinical problems can be resolved through optimal clinical evidence is closely combined with clinical experience and patient＇s condition to find and collect optimal clinical evidence, pay attention to the accuracy of clinical evidence and Meta-analysis.