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复方中药组方抗前列腺炎的实验研究 被引量:6

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摘要 目的研究复方中药组方以及它对实验性前列腺炎的治疗作用。方法采用U9(98)均匀设计方法,将8味药材按不同配比组方,通过对卡拉胶所致大鼠急性前列腺炎模型中前列腺指数的影响,优化配方。将优化的配方按高(5 g/kg)、中(3 g/kg)和低(1.5 g/kg)剂量灌胃给药,通过消痔灵所致大鼠慢性前列腺炎模型观察,结合鼠耳抗炎性实验,探讨配方对前列腺炎的作用。结果不同配方给药组前列腺指数均显著低于模型组(P<0.01),优化后配方为绿茶9 g,淡竹叶1g,蒲公英9 g,茯苓3 g,赤小豆5 g,黄精9 g,山药9 g。该组方高剂量组对慢性前列腺炎大鼠前列腺指数、白细胞数和卵磷脂小体密度较模型组均有显著的影响(P<0.05),抗炎效果显著(P<0.05)。结论该配方具有显著抑制实验性前列腺炎的作用。
出处 《时珍国医国药》 CAS CSCD 北大核心 2012年第9期2195-2196,共2页 Lishizhen Medicine and Materia Medica Research
基金 广东省部产学研结合项目(No.2010B090400515)
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