基于HIS系统的真实世界的59287例疏血通注射液临床实效研究

Clinical outcomes research of Shuxuetong injection based on 59 287 cases in hospital information system

目的:采用频数分析的方法分析信息管理系统(hospital information system,HIS)中使用疏血通注射液患者的相关指标分布情况,以便了解真实世界中使用疏血通注射液的患者群情况,为临床应用提供参考和指导。方法:选择全国20家三甲医院使用疏血通注射液的住院患者信息,参照集成数据仓库构建模式,使用频数分析方法对使用疏血通注射液的患者选取其人群特征、性别、住院费别、给药科室、给药途径、合并用药等方面进行描述分析;采用关联规则方法统计患者合并用药的分布情况。结果:在HIS数据库中使用疏血通注射液患者的平均年龄为59岁,年龄分布的2个峰值,分别是56,71岁;享有医保或国家其他医疗保险的患者占有效信息的75.8%;95.76%的信息显示给药途径采用静脉滴注方式;患者人群常被诊断为高血压、脑梗死和冠心病等心脑血管疾病;其合并用药多以阿司匹林、胰岛素、肝素等为多;临床多选择0.9%氯化钠注射液做为溶媒。结论:使用疏血通注射液的人群以中老年人群为主,并以医保患者或享有国家医疗保险等相关政策的患者居多。给药途径基本符合药品说明书,多作为治疗心脑血管疾病或糖尿病的联合用药,但请临床医生注意并重视患者的受益与风险比。

Objective： In order to find out the condition of patients who used the Shuxuetong injection and provide reference and guidance for clinical practice, we analyzed the data of related indicators in patients in the HIS based of the frequency analysis methods. Method： In this study, we selected the hospitalized patient information in 20 hospital information systems （HIS）. Reference to the integrated data warehouse build mode, including some information such as age, gender, cost categories of patients, route of administration etc. Result： The average age of patients are 59-years-old , 56-years-old age and 71-years-old age are the two high peaks during the age distribution. Patients covered by health insurance accounted for 75.8% ; Intravenous infusion in patients accounted for 95.76% ; Patient are also diagnosed as cardiovascular and eerebrovaseular diseases, such as hypertension, cerebral infarction, coronary heart diseas, combined with other medicines such as aspirin, insulin, heparin etc. Conclusion： Crowd using Shuxuetong injection mostly in the elderly population, most patients covered by health insurance, the route of administration conforms instructions basically, please attention the benefits and risks of the patients in the clinical practice.