摘要
中药引起的不良反应问题已越来越引起人们的高度重视。中药注射剂在生产、配制及输注过程中可能产生不溶性微粒,是引发部分药物不良反应如静脉炎、过敏反应等的原因之一,因此如何控制中药注射液中的不溶性微粒输入人体对于安全用药至关重要,笔者从对输液微粒的认识、中药注射剂与液体配伍后不溶性微粒增加的现象及原因分析、普通输液器与精密输液器的优缺点比较等方面查阅了大量的文献资料。发现控制中药注射液中的不溶性微粒输入血管,从而降低部分中药注射剂药物不良反应的发生,常规采用精密过滤输液器输注中药注射剂是最理想、最有效、最安全的输液方式。
The adverse reactions caused by the traditional Chinese medicine has become increasingly aroused great attention. Traditional Chinese medicine injection may produce insoluble particles in the process of production, preparation and infusion, which is one of the reasons caused some adverse drug reactions such as phlebitis, allergic reactions, so it is essential that how to control Chinese medicine injection of insoluble drug particles enter human clinical safety. The author retrieve a large number of paper, from the infusion of particles, analysis traditional Chinese medicine injection and insoluble particles in the liquid compatibility increased occurrence and cause, comparative advantages and disadvantages of the ordinary infusion and precision infusion, which found that using sophisticated filters infusion of traditional Chinese medicine injection control of traditional Chinese medicine injection of insoluble particles enter the blood vessels, thereby reducing the occurrence of adverse drug reactions part of the traditional Chinese medicine injection, is the best, most effective, most secure way of infusion.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第18期2758-2759,共2页
China Journal of Chinese Materia Medica
基金
国家"重大新药创制"科技重大专项(2009ZX09502-030)"中药上市后评价关键技术研究"
关键词
不溶性微粒
精密输液器
中药注射剂
insoluble particle
precise infusion apparatus
traditional Chinese medicine injection