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钌催化芳香硝基化合物和脂肪三级胺反应一锅法合成喹啉衍生物 被引量:2

Ruthenium-Catalyzed One-Pot Synthesis of Quinolines from Nitroarenes and Trialkylamines
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摘要 以芳香硝基化合物和脂肪三级胺为原料,三环己基膦四氟硼酸盐为配体,在三氯化钌催化下"一锅法"合成了一系列喹啉衍生物.该法不需要添加任何额外的还原剂,原料便宜易得,操作工艺简单,产率中等.产物结构通过IR,1H NMR,13C NMR,MS以及元素分析表征. A series of quinolines were synthesized in moderate yields by one-pot reaction of nitroarenes and trialkylamines in the presence of a catalytic amount of ruthenium trichloride catalyst together with tricyclohexylphosphonium tetrafluoroborate ligand. This method is convenient without extra reductant, and nitroarenes are cheap and highly available. The structures of the products were characterized by IR,^1 H NMR,^13C NMR, MS techniques and elemental analysis.
出处 《有机化学》 SCIE CAS CSCD 北大核心 2012年第9期1725-1731,共7页 Chinese Journal of Organic Chemistry
基金 国家自然科学基金(No.20902076)资助项目~~
关键词 C-N键形成 一锅法 喹啉衍生物 钌催化 硝基芳烃 三级胺 C--N bond formation one-pot synthesis quinolines ruthenium catalyst nitroarenes trialkylamines
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