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不停跳心内直视术中P-选择素在肺循环的表达研究

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摘要 目的:观察不停跳心内直视术下P-选择素在肺循环中的表达。方法:将室间隔缺损患者28例,随机分成停跳组14例,行停跳体外循环下室间隔缺损修补术。不停跳组14例,行不停跳体外循环下室间隔缺损修补术。于转机前(T1)、转机20min(T2)、转机末(T3)、转机结束15min(T4)分别自肺静脉采血,采用酶联免疫吸附法检测血中P-选择素的表达并作出对比分析。结果:体外循环前、后患者P-选择素表达变化差异有统计学意义(F=416.622,P<0.01);组内比较P-选择素表达随时间的变化具有递增性,差异均具有统计学意义(F=29.543,P<0.01);组间同一时间检测点的比较,体外循环后不停跳组P-选择素的水平均低于停跳组,差异有统计学意义(P<0.05)。结论:心内直视术下P-选择素在肺循环中表达增强,但在不停跳体外循环下的表达增强程度要弱于停跳体外循环下。
出处 《广西医科大学学报》 CAS 2012年第4期553-555,共3页 Journal of Guangxi Medical University
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