抗肿瘤药物的不良反应报告分析

Anticancer Drugs Adverse Reaction Reports

目的了解抗肿瘤药物不良反应(ADR)的发生特点及规律,为临床安全用药提供参考。方法回顾性分析65例抗肿瘤药物ADR患者的临床资料。结果 65例ADR中,男37例,女28例,50岁以上45例,占69.23%。抗肿瘤植物药引起的不良反应发生率排首位,共23例,占35.38%。变态反应25例和消化系统反应18例,分别占38.46%和27.69%。结论应加强监测抗肿瘤药物ADR,做好防治,合理使用。

Objective To inversitigate the laws and characteristics of adverse drug reactions（ADR） of antineoplastic drugs occurred and to provide references for safe use of antineoplastic drugs clinically.Methods 65 cases with ADR of antineoplastic drugs collected were analyzed retrospectively.Results In all of the 65 ADR cases,37 were male and 28 were female.The incidence of ADR occurred in the patients older than 50 was 45（69.23%）.The incidence of ADR of anti-tumor botanical drugs was the highest（40.31%）,25 cases of allergic（38.46%）,18 cases of gastrointestinal reactions（27.69%）.Conclusion Monitoring of ADR of antineoplastic drugs should be strengthened and preparing the prevention and treatments for ADR in order to rational use.