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自噬与肿瘤

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摘要 自噬(autophagy)是细胞的溶酶体降解途径,广泛存在于大多数真核细胞中,对维持真核细胞内环境的稳定和新陈代谢起重要作用,但也可诱导真核细胞发生程序性细胞死亡,并称之为2型程序性死亡。自噬涉及一系列复杂的分子机制和信号调控,目前尚未完全研究清楚。近年来的研究发现,自噬与肿瘤等疾病的发生发展密切相关,对肿瘤细胞起到了抑制和保护的双重作用,并可能因此成为肿瘤治疗的潜在靶点。
作者 汪蓉
出处 《中国医药指南》 2012年第25期79-80,共2页 Guide of China Medicine
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参考文献7

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