摘要
目的建立胃肠康定胶囊的质量控制方法。方法采用TLC法鉴别方中黄连、延胡索、三七;采用HPLC法对芍药苷进行含量测定。结果本品定性鉴别薄层色谱特征明显,专属性强;芍药苷在0.0636～1.272μg的范围内线性关系良好(r=1),平均回收率为98.15%,RSD=1.32%(n=6)。结论所建立的方法简单,准确,重复性好,可作为胃肠康定胶囊的质量控制标准。
Objective To establish the quality standard for Weichaug Kangding Capsule. Methods TLC was used to identify Rhizoma Coptidis, Rhizoma Corydalis, Radix Notoginseng. HPLC was used to determine paeoniflorin. Results The characteristics for identification by TLC were distinct and highly specific, and paeoniflorin could be determined by HPLC. The linearity of paeoniflorin was good in the range of 0.0636- 1.272 ug （r=1）. The average recovery of paeoniflorin was 98.15 % and RSD was 1.32 %（n=6）.Conclusion The method developed is simple and accurate with reproducibility. It can be used for quality control of Weichang Kangding Capsule.
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2012年第5期582-585,共4页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
山西省科技攻关项目(20080311054-1)
关键词
黄连
延胡索
三七
芍药苷
质量标准
Rhizoma Coptidis
Rhizoma Corydalis
Radix Notoginseng
Paeoniflorin
Quality standard
