1635例肺癌术后患者电话随访结果及预后分析

Telephone follow-up of 1635 post-surgery lung cancer patients and retrospective study of lung cancer prognosis

目的：分析肺癌患者术后的电话随访结果及影响肺癌预后的因素，探讨提高电话随访成功率的方法。方法：2011年11月至2012年1月对2002年1月至2011年8月期间1635例本院肺癌手术患者进行电话随访。随访结果及临床资料汇总后进行统计分析，在其中116例临床资料完整的病例中，进一步探讨肺癌转移和长期生存率的影响因素。结果：平均随访成功率为36．1％，电话随访成功率与术后随访间隔时间相关，随访时间与手术间隔时间越近，随访成功率越高。女性患者随访成功率要明显高于男性患者（P〈0．001）。40岁以下患者的随访成功率（56％）明显高于50～59岁及60岁以上患者（分别为39％和24％，P〈0．001），城镇和农村的随访成功率差异无明显统计学意义（P=0．844）。在116例临床资料完整的病例中，统计验证了转移和高淋巴结分期增加术后死亡的风险（OR值分别为o．212和1．818），腺癌、淋巴结高分期、高龄与术后肿瘤转移相关（OR值分别为2．353，2．181和2．908）。结论：电话随访成功率受时间、年龄及性别等因素影响。在小样本的病例分析中验证了远处转移、淋巴结转移、病理类型及高龄与肺癌预后的关系。

Objective： To evaluate the telephone follow-up of surgery patients with lung cancer and to analyze the prognosis factors. Methods： From October 2011 January 2002 to August 2011we and clinical characteristics were complete and reliable clinical data were further cancer metastasis and long-term survival. analyzed to determine the effective factors of lung Results： The average response rate in the follow-up was 36.1%, and the response rate was related to the interval time after the operations. The shorter the interval, the higher the response rate. The response rate in female patients was higher than that in male patients （P〈0.001）.The response rate was higher in patients younger than 40 （56 %） than that inthe patients aged between 50-59 and over 60 （39% and 24% respectively, P〈0.001）. There was no statistical difference between patients from urban and rural areas （P=0.844）. In the 116 patients with complete and reliable clinical data, statistical analysis confirmed that the metastasis and high lymph node staging were factors to increase patients risk of death （with odd ratio 0.212 and 1.818 respectively, P〈0.001）. The adenocarcinoma grade, high lymph node staging and advanced age were related to the metastasis risk （odds ratio 2.353, 2.181 and 2.908, respectively）. Conclusion： Time, gender and age are the influencing factors in the telephone follow-up. Metastasis, lymph node metastasis, pathologic type and age are related to the lung cancer prognosis in the small-scale sample.