八仙花中酚酸类化学成分的结构鉴定

Study on Chemical Constituents from the Hydrangea macrophylla(Thunb.) Ser

目的:分离、鉴定八仙花提取物中的酚酸类化学成分。方法:采用硅胶柱、ODS开放柱和制备液相等色谱方法分离,并通过NMR和MS等谱学技术确定结构。结果与结论:从八仙花提取物中分离得到6个酚酸类化合物,分别为香草醛(1),异香草醛(2),异香草酸甲酯(3),9-甲氧基-异丁香酚(4),香豆酸甲酯(5),对羟基苯甲醛(6)。

Objective：To investigate the chemical constituents of the extract from the Hydrangea macrophylla （Thunb.） Ser. Methods：The chemical constituents were isolated by various isolation methods （ silica gel, ODS and HPLC column chromatography） and their structures were elucidated by the analysis of spectral data （ NMR and MS）. Results and Con- clusion ：Six compounds were obtained and elucidated as following： vanillin （1） , isovanillin （2） , isovanillic acid methyl ester （ 3 ）, 9 - methoxy - isoeugenol （4）, methyl - p - coumarate （5）, 4 - hydroxybenzaldehyde （6）.