摘要
目的:探讨I型Hp感染对2型糖尿病视网膜病变的影响及感染率。方法:对130例确诊2型糖尿病患者进行眼底照相诊断,根据有无视网膜病变分为两组,70例有并发视网膜病变组(DR组)和60例无并发视网膜病变组(NDR组)及正常对照组50例,采用免疫印迹法测定有无Hp感染,对2型糖尿病患者进行血脂、糖化血红蛋白(HbA1c)测定。结果:130例2型糖尿患者中Hp感染者58例(44.61%),其中70例DR组中Hp感染者36例(51.42%),60例NDR组中Hp感染者22例(36.66%)。50例正常对照组中Hp感染者18例(36.00%)。DR组Hp感染率高于正常组和DR组,比较差异具有统计学意义(P<0.05),NDR组与正常组Hp感染率比较差异无统计学意义(P>0.05);DR组HbA1c、TG、CHO、LDL-C均明显高于对照组和NDR组(P<0.05)。结论:2型糖尿病患者Hp感染率高于正常人,尤其是伴有视网膜病变者;Hp感染与DR、糖化血红蛋白增高、脂代谢紊乱的发生可能有一定的相关性。
Objective:To study the type I Hp infection in type 2 diabetic retinopathy and investigate infection rates of the type I Hp.Method:130 patients diagnosed type 2 diabetes patients with diagnosis of diabetes, according to whether retinopathy was divided into two groups:70 cases had concurrent retinopatby group(DR group)and 60 cases of no concurrent fox lesions group(NDR group)and normal control group 50 patients, the immunoblot method to determine whether Hp infection, in type 2 diabetes patients for blood lipid, glycated hemoglobin(HbAlc)was in statistical analysis.Resuit:130 cases of type 2 diabetes patients Hp infections 58 cases(44.61%), 70 patients with DR group Hp infections 36 cases(51.42%), 60 cases NDR group Hp infections 22 patients(36.66%) ; 50 cases the control group Hp infections 18 cases(36.00%), lip infection rates of DR group higher than normal control group and NDR group(P〈0.05), Hp infection rates of NDR group compared with normal control no difference(P〉0.05).HbAlc, TG, CHO, LDL-C of DR group were significantly higher than those in the control group and NDR group(P〈0.05 or P〈0.01). with type 2 diabetes Hp infection rates higher than normal, especially those with retinopathy ; Hp infection and DR, glycated hemoglobin rising and lipid metabolism disorders may have a certain correlation occurred.
出处
《中国医学创新》
CAS
2012年第26期11-12,共2页
Medical Innovation of China