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非甾体类消炎药相关性胃溃疡的临床特点分析 被引量:5

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摘要 目的:探讨非甾体类消炎药(NSAIDs)相关性胃溃疡的临床诊治特点。方法:收集62例NSAIDs相关性胃溃疡患者进行回顾性分析,总结其临床特点。根据治愈后是否维持治疗分成维持治疗组和未维持治疗的对照组,随访半年观察溃疡的复发情况。结果:62例溃疡患者平均年龄(63±9.8)岁,有14例合并Hp感染,其中因腹痛就诊12例,消化道出血36例,穿孔2例,胃肠道感染9例,营养不良及其他原因3例。经治疗后60例治愈(其中56例内科保守治疗,4例经手术治疗),2例溃疡未愈合。60例治愈患者中有44例继续PPI联合胃黏膜保护剂维持治疗,随访半年后有5例溃疡复发,另16例未维持治疗患者有9例复发。结论:NSAIDs相关性胃溃疡老年人多发,与Hp感染无关,常以消化道出血为首发症状。PPI联合胃黏膜保护剂维持治疗有助于预防溃疡的复发。
作者 谈燕群
出处 《中国医学创新》 CAS 2012年第26期128-129,共2页 Medical Innovation of China
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