鱼类尾部神经分泌系统研究进展

Research progress on the caudal neurosecretory system of fish

尾部神经分泌系统是鱼类特有的神经分泌系统,位于脊髓末端,是鱼类适应环境的关键。该系统作为应激系统的一部分,在鱼类生理和行为方式等多方面具有综合调节作用。综述了自19世纪末尾部神经分泌系统被发现以来,尤其是近年来生物学家在该系统形态结构及组成、主要内分泌细胞(Dahlgren细胞)及其分泌物的功能和生理调节、神经支配等方面的研究成果,以及一些环境变化引起的应激反应与尾部神经分泌系统的相关性的研究。为研究该系统相关分泌肽及其功能提供更为广泛的参考,同时为进一步了解相关分泌肽在高等脊椎动物甚至人类中的功能提供借鉴。

The caudal neurosecretory system（CNSS） is a unique neuroendocrine system of fish,which located at the caudal spinal cord.CNSS is the key for fish to adapt the environment.As a part of the stress system,CNSS plays comprehensive regulatory role in fish physiology and behavior.Here,we reviewed morphology and composition of this system,its main secreting products,and their role in physiological regulation and innervation since the end of the 19th century when CNSS was found.All of these will provide scientific basis for further studying on neural secretions in higher vertebrates,and even for understand the functions of neurosecretory materials in human.