糖化血红蛋白与2型糖尿病患者慢性并发症的相关性研究

Glycosylated Hemoglobin and Chronic Complications of Type 2 Diabetes

目的探讨糖化血红蛋白(HbA1c)水平与2型糖尿病患者慢性并发症的相关性。方法 92例2型糖尿病患者按有无慢性并发症分为慢性并发症组52例和无慢性并发症组40例,另选70例健康成年人为对照组,对三组对象进行HbA1c、空腹血糖(FBG)测定,并进行分析比较。结果 2型糖尿病患者的HbA1c和FBG明显高于对照组,差异有统计学意义(P<0.01);有慢性并发症患者的HbA1c明显高于无并发症者,差异有统计学意义(P<0.01)。结论糖尿病患者慢性并发症的发生与HbA1c有密切关系,HbA1c的控制有助于预防糖尿病及其慢性并发症的发生。

OBJECTIVE Explore glycated hemoglobin（HbA1c）control and chronic complications of type 2 diabetes.METHODS 92 cases of type 2 diabetes without chronic complications divided into 52 cases of chronic complications and chronic complications of 40 cases,70 cases of healthy adults as a control group of HbA1c,fasting blood glucose（FBG） measurement,were analyzed.RESULTS Type 2 diabetes patients with HbA1c and FBG showed a significant positive correlation,the difference was statistically significant（P〈0.01）.Type 2 diabetes with chronic complications in patients with HbA1c was significantly higher than those without complications,the difference was statistically significant（P〈0.01）.CONCLUSION Chronic complications of diabetes patients with HbA1c,HbA1c control,helps prevent diabetes and its chronic complications,development,and improve the quality of life of patients with type 2 diabetes in the community are very important.