克山病监测之转化流行病学

The translational epidemiology of Keshan disease surveillance

将流行病学基本理论和技术规范地应用到疾病监测和防控实践,是疾病监测和防控实践最基本的转化流行病学和创新。能够发现疾病监测和防控实践中的新问题,并能够以新技术解决问题,是高一个层次的转化流行病学和创新。为解决实践中的关键问题,发明新技术或促进了疾病监测和防控理论和方法的发展,则是很高层次的转化流行病学和创新。10年来,我们要求克山病病区省上报克山病监测的原始数据,以PPS方法调查克山病患病率,通过增加病例搜索改进哨点监测方法,调查非病区扩心病患病水平,这些都是对我国克山病防控实践的深刻思考后,自觉或不自觉地将转化研究的理念应用于中国克山病监测的实践。

Appropriately applying the theory and methods of epidemiology to the practice of disease surveillance, prevention and control is the most fundamental translational epidemiology and innovation. Being able to find and solve the key issues in the practice of disease surveillance, prevention and control by applying new technology is one tier higher translational epidemiology and innovation. It is very high level of translational epidemiology and innovation if the theory and methodology are advanced by creating new technology in finding out and solving the key /. issues in the practice of disease surveillance, control and prevention. In the past ten years, we required the provinces with endemic areas of Keshan disease submitting the original surveillance data, surveyed the national prevalence of Keshan disease with the method of PPS, improved the method of sentinel surveillance by adding case-searching to identify the sentinel sites, and surveyed the prevalence of dilated cardiomyopathy in non-Keshan disease endemic areas. All these are the conscious or unconscious applying of translational researches to the practice of Keshan disease surveillance after careful considering the key issues of Keshan disease surveillance, prevention and control in China.