超声联合钼靶X线检查在乳腺良恶性肿瘤鉴别诊断中的应用

Combination of ultrasonography and X-ray mammography in differential diagnosis of benign and malignant breast tumors

目的评价超声联合钼靶X线检查在乳腺良恶性肿瘤鉴别诊断中的应用价值。方法经病理证实的168个乳腺肿瘤术前均行超声及钼靶X线检查,评估两种诊断方法及联合应用的灵敏度、特异度、阳性预测值、阴性预测值及诊断符合率。结果 168个乳腺肿瘤中,良性113个,恶性55个。除钼靶对恶性肿瘤钙化的显示率高于超声之外(P<0.01),两者在其余指标的检测差异均无统计学意义(P>0.05)。二者联合诊断乳腺良恶性肿瘤的特异度、阳性预测值及符合率均优于单用超声、钼靶,差异均有统计学意义(P<0.01或0.05)。结论超声和钼靶X线联合应用可显著提高乳腺肿瘤的诊断符合率。

Objective To evaluate the feasibility of ultrasonography and X-ray mammography in the differential diagnosis of benign and malignant breast tumors. Methods Based on the pathological results, the sensitivity, specificity, positive and negative predictive value, and accuracy of ultrasonography and/or X-ray mammography were evaluated in 168 breast neoplasms. Results There were 113 benign and 55 malignant breast tumors. Although the mammography was superior to ultrasonography in the detection of calcification of malignant tumors （P〈0.01）, other indexes showed no significant difference between both methods （P〉0.05）. The specificity, positive predictive value and diagnostic accuracy were significantly higher in the combination of ultrasonography and mammography than those in single use of them （P〈0.01 or 0.05）. Conclusion The combination of ultrasonography and mammography can improve the diagnostic accuracy of breast tumors.