中心动脉压——降压治疗新靶点

Central Aortic Pressure:A New Antihypertensive Target

降压治疗能降低心脑血管疾病的发生率和病死率,保护心脑肾等靶器官。一直以来,血压控制目标均是基于外周肱动脉压。但是目前有研究显示,中心动脉压较外周肱动脉压与心脑肾等靶器官损害的关系更为密切,降低中心动脉压能进一步减少心血管事件发生率,保护靶器官。而且目前已有无创的准确测量中心动脉压的仪器,为降低中心动脉压治疗提供了基础。中心动脉压或许能成为降压治疗的新靶点,本文就此问题进行综述。

Antihypertensive therapy can reduce the incidence and mortality of cardiovascular and cerebrovascular dis- eases and protect target organs such as heart, brain and kidney. All along, the target of control blood pressure is based on pe- ripheral brachial artery pressure. But recent studies have indicated that central aortic pressure has a closer relation with damages of target organs than peripheral brachial artery pressure and its reduction can decrease further incidence of cardiovascular events to protect target organs. And now non - invasive instruments measuring directly the central aortic pressure provide basis for its treat- ments. Central aortic pressure mar be a new target for antihvoertensive treatment.