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Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes

Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes
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摘要 A research team led by Professor He Xionglei at the College of Life Sciences,Sun Yat-sen(Zhongshan) University made a breakthrough in understanding how chromatin structure regulates spontaneous mutations,with a discovery that nucleosomes,the structural units of chromatin,suppress mutations from cytosine(C) to thymine(T) in eukaryotic cells.This research appears as a Report in the March 9^(th) issue of Science. Mutations not only provide new materials for evolution,but also are the primary cause of diseases. A research team led by Professor He Xionglei at the College of Life Sciences, Sun Yat-sen (Zhongshan) University made a breakthrough in understanding how chromatin structure regulates spontaneous mutations, with a discovery that nucleosomes, the structural units of chromatin, suppress mutations from cytosine (C) to thymine (T) in eukaryotic cells. This research appears as a Report in the March 9th issue of Science.
出处 《Science Foundation in China》 CAS 2012年第1期23-23,共1页 中国科学基金(英文版)
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