慢性胰腺炎430例诊治分析

The diagnosis and treatment of chronic pancreatitis in 430 cases

目的调查云南省慢性胰腺炎的诊断和治疗。方法回顾性分析云南省6所省市级综合医院(2003年1月至2010年12月)8年间确诊为慢性胰腺炎(CP)430例患者的影像学检查资料和内科治疗、内镜治疗及手术治疗。结果 430例CP患者中,CT、MRI、MRCP阳性率较高,分别为96.9%、96.1%、94.4%;灵敏度较高,分别为96.3%、96.2%、96.1%。内科治疗者占80.5%,其中以使用抑酸剂者最多(占89.9%),使用胰酶制剂者次之(占33.8%);外科治疗者占40.5%,以采用胰肠Roux-en-Y吻合术式者最多(69.2%);内镜介入治疗者最少(4.4%)。结论对于云南省的CP患者,CT、MRI、,MRCP阳性率较高、灵敏度较高,可作为诊断CP的首选影像学检查。目前治疗仍以内科治疗为主,外科治疗次之,内镜介入治疗最少。

Objective To investigate the diagnosis and therapy for chronic pancreatitis in Yunnan Province. Methods Imaging examination material,medical therapy,interventional endoscopic therapy and surgery of 430 patients with chronic pancreatitis treated in Six provincial and municipal general hospitals of Yunnan Province between eight years（2003-01-01/2010-12-31）were retrospectively analyzed. Results In 430 eases of CP patients,positive rate of CT, MRI, MRCP was higher,they were 96.9 %, 96.1%, 94.4 % ;their sensitivity is higher, they were 96.3 %, 96.2 %, 96.1%. The medical treatment for 80.5 %, in which taking the antacid took the most （89. 9 %）, taking the pancreatic enzyme preparation take second place（33.8%） ; Surgical treatment for 40. 5 %, in witch adopting pancreatic bowel Roux-en-Y took the most（69.2 %） ;Endoscopic intervention was few（4.4%）. Conclusion For the patients with CP in Yunnan Province, positive rate and sensitivity of CT, MRI, MRCP are higher, which can be used as the first choice of CP imaging diagnosis. The treatment of CP at present still is medical treatment given priority to,surgical treatment is the second smallest, and endoscopic intervention is few.