硬膜外阻滞镇痛应用于分娩镇痛428例的临床研究

Clinical observation of epidural analgesia for labor pain in 428 cases

目的探讨分娩镇痛的安全性、效果及对产程、母婴的影响。方法回顾本院2010年11月至2011年4月采用硬膜外给药方式行分娩镇痛病例428例与同期未行分娩镇痛病例111例对比,观察镇痛效果、产程时间、分娩方式、产后出血的情况,以及会阴裂伤及新生儿窒息发生率。结果行分娩镇痛组与未行分娩镇痛组比较,镇痛效果确切,分娩镇痛组潜伏期延长,会阴裂伤发生率降低(P<0.05),总产程、产后出血及新生儿窒息的发生率比较差异无统计学意义(P>0.05)。对剖宫产率是否增高的影响尚不明确。结论硬膜外镇痛的使用安全有效,对母婴无明显不良影响,值得推广。其是否延长产程、提高剖宫产率尚需进一步研究。

Objective To study the safty,effectiveness of epidural analgesia for labor pain and its influence on the labor course, and patients. Methods The clinic data from Nov. 2010 to Apr. 2011 were analysed to detect the differences between the epidural analgesia group and non-epldural analgesia group on labor course, delivery mode, incidence of postpartum hemorrhage, neonatal asphyxia. Results The epidural analgesia group had a prolonged latency and higher incidence of cesarean saction,but lower incidence of perineal laceration（P〈0.05）. There were no significant differences on the total stage of labor,incidences of postpartum hemorrhage and fetal asphyxia（P〉0.05）. Conclusion Eepidural analgesia for labor pain is safe,effective,and harmless for patients. It is worth popularizing. But more research were needed to find whether the epidural analgesia prolonged latency and make higher inci denee of cesarean saction.