转化医学时代的生殖医学研究——挑战与展望

Reproductive Medicine Research in the Era of Translational Medicine:Challenges and Perspectives

转化医学是一个理念及研究战略,不是一句口号和一个标签,人民的公共卫生需求是转化医学的出发点与归宿。当前中国生殖医学的研究重点领域包括:避孕节育,不孕不育,辅助生殖技术,出生缺陷与出生质量,生殖系统疾病以及环境对生殖健康的影响。转化医学的关键在于转化,包括从临床需求转化为基础研究课题,也包括将基础研究的结果转化为临床诊疗新途径。当前辅助生殖技术的转化医学研究中有3个重点:①如何提高辅助生殖技术的成功率。②如何减少辅助生殖技术对母体和子代可能带来的风险。③如何建立辅助生殖研究与应用中的伦理规范。

Translational medicine is an idea and major research strategy,rather than a slogan or a label. People＇s needs and demands in public health is the starting point of translational medicine. The priority areas of reproductive medicine in China are：development of new contraceptives,prevention and management of infertility,assisted reproductive technology （ART） development and application,birth defects and birth quality, prevention and management of reproductive tract infections （RTIs） and reproductive tract cancer,alleviation of impacts of environment and life styles on reproductive health. The key to translational medicine is to facilitate the transitions from public health problems into basic and laboratory studies, as well as from research results of basic and laboratory studies into clinic diagnosis,treatment and optimal clinic pathway. In the field of ART, there are three major research priorities：how to improve the successful rate of ART,how to satisfy the ART safeties of both mother and offspring, and how to develop the bioethieal guideline of ART. Chinese scientists should ,can and must make our contribution in the era of translational medicine.