辅助生殖技术中的月经周期与卵巢周期的新理念

Menstrual Cycle and A New Concept of Ovarian Cycle in Assisted Reproductive Technology

月经周期反映周期性卵泡发育、排卵及黄体形成的过程,该过程受到下丘脑-垂体-卵巢轴的内分泌调节,这一生理调节过程是非常精确的。随着年龄的增长,这一调节的精确度逐渐下降,对于年长妇女进行辅助生殖技术(ART)显得更为重要。从近年ART的实践观察卵泡发育与排卵体现卵巢周期比传统的月经周期更具挑战性。一种新的技术即月经期或黄体期可以随时取卵,以提高妊娠率。

Menstrual cycle is a mirror which reflects the follicle development,ovulation and luteinization. This cycle is precisely regulated by the hypothalamic-pituitary-ovary axis. In aged women, this regulation becomes less and less precise with aging, which seems to be more important for those aged women undergoing ART. For ART, it is important that we should understand a new concept of ovarian cycle. This is a challenging concept for the observation of follicle development and ovulation. A new technique, ovum pick up whenever lutein phase and menstrual period, can be used to improve the pregnant rate.