摘要
斑马鱼是生物钟研究领域中一种新兴的脊椎动物模型。文章总结了斑马鱼生物钟研究的一些进展,以及利用斑马鱼研究生物钟的特点及优势。由于光照和温度作为重要的外部信号在斑马鱼生物钟调节中发挥重要作用,文章主要就近期光和温度对斑马鱼钟基因及调节通路的研究进行了概述,最后对斑马鱼生物钟研究的未来提出了展望。
Zebrafish has recently become an emerging vertebrate model for circadian studies. Here we summarized recent advances in the field of zebrafish circadian research. The characteristics and advantages of zebrafish as a circadian model, as well as its time-keeping mechanisms, were highlighted. Because light and temperature as external time cues both play important roles in the circadian regulation of zebrafish, we focused on recent studies concerning the effects of light and temperature on circadian clock genes and circadian regulatory pathways in zebrafish. We also provided the perspectives on prospective zebrafish circadian studies.
出处
《遗传》
CAS
CSCD
北大核心
2012年第9期1133-1143,共11页
Hereditas(Beijing)
基金
国家自然科学基金重点项目(编号:310300062)
国家重大科学研究计划(编号:2012CB947600)
江苏特聘教授计划和苏州大学科研启动经费(编号:Q4134918)资助
关键词
生物钟
负反馈环路
光调节
温度补偿
斑马鱼
circadian clocks
negative feedback loop
light regulation
temperature compensation
zebrafish