嘉定镇社区卫生服务中心药品不良反应99例分析

Analysis of the adverse drug reactions of 99 cases in community health service centre of Jiading town

目的:为了解嘉定镇社区卫生服务中心药物不良反应发生的特点及规律,促进社区医生规范合理用药。方法:采用回顾性调查方法,对2009-2010年本中心发生的99例药物不良反应进行统计分析。结果:99例ADR报告中,60岁以上老年人、联合用药、抗菌药、静脉给药ADR的发生率分别为89.90%、46.47%、54.55%;ADR表现以皮肤、黏膜和神经系统损害为主。结论:应加强对老年人ADR的监测,合理选择抗菌药物及给药途径,加强合理用药的宣传,可有效地减少ADR的发生。

Objective： To learn the characteristics and regularity of the adverse drug reactions in the community health service center to promote the clinician＇s regulation of the rational use of medicines. Method： The adverse reactions of 99 cases were statistically analyzed with the retrospective survey method from 2009-2012 in the health service centre. Result： In the ADR reports of 99 cases, the elderly over 60 years old, the incidence of a combination of medication, antimicrobial agents, intravenous administration were 89.90%, 55.56%, 46.47% and 54.55%, respectively. The manifestations were mainly the skin, mucosa and nervous system damages. Conclusion： It should be strengthened to monitor the elderly adverse drug reactions, to reasonably choose the antibacterial drugs and route of administration, and advocate the reasonable use of drugs so as to effectively reduce the occurrence of ADR.