聚肌胞注射液联合针刺治疗多发性跖疣的效果

THE EFFECT OF LOCAL INJECTION OF POLYINOSINIC-POLYCYTIDYLIC ACID COMBINED WITH ACUPUNCTURE IN THE TREATMENT OF MULTIPLE PLANTAR WARTS

目的观察聚肌胞注射液联合针刺治疗多发性跖疣的效果。方法将门诊154例多发性跖疣病人随机分为2组。治疗组78例,注射聚肌胞,并对病变部位进行针刺治疗;对照组76例,采用液氮冷冻疗法,两组均间隔15d治疗1次,连续治疗3次。比较两组临床疗效及创面愈合时间,对痊愈病人于治疗结束后3个月进行复发率的评价。结果治疗组总有效率、复发率及创面愈合时间分别为87.18%、8.33%、(10.43±2.44)d,对照组分别为71.05%、22.58%、(13.46±3.20)d,两组比较差异均有统计学意义(χ2=6.081、5.325,t=6.398,P<0.05)。结论聚肌胞注射液联合针刺治疗多发性跖疣疗效可靠、复发率低、创面恢复快,值得临床推广应用。

Objective To observe the therapeutic efficacy of polyinosinic-polycytidylic acid （Poly I C） injection combined with acupuncture for multiple plantar warts （MPW）. Methods This study consisted of 154 patients with MPW, who were randomized to treatment group （78 cases） and control group （76 cases）. The patients in the treatment group were treated with local inieeion of poly I-C combined with acupuncture; those in the control group were treated with liquid nitrogen cryotherapy. The course of both groups was once every I5 days for three treatments. The curative effect and healing time of raw surface were compared between the two groups, and for those fully recovered were reviewed at three months after completion of the therapy in terms of receurence rate. Results The total effective rate, reccurence rate, and time of healing in patients of treatment group were 87. 18%, 8.33%, and （10.43±2.44） days, respectively, and that in the control were 71.05%, 22.58%, and （13.46±3. 120） days, the differences were significant between the two groups （x^2=6.081,5.325;t=6.398;P〈0.05）. Conclusion The effect of Poly I-C injection combined with acupuncture for MPW is reliable with low reccurence and fast healing of raw surface, which is worthwhile in clinical application.