摘要
目的:探讨熵权系数法在评价临床抗老年痴呆精神类药物治疗效果中的作用。方法:选取我院2009年1月至2011年7月收治的167例老年痴呆患者,随机分为利培酮组(21例)、石杉碱甲组(25例)、多奈哌齐组(24例)、奥氮平组(27例)、奥氮平联合利培酮组(24例)、奥氮平联合石杉碱甲组(22例)、奥氮平联合多奈哌齐组(25例)。治疗8周后,选择痴呆病理分析评定(Behave-AD)、简易智力状况检查评分(MMSE)、日常生活活动能力(ADL)为评价指标,采用熵权系数法进行治疗效果的综合评价。结果:奥氮平联合利培酮具有最佳治疗效果,单用利培酮的效果则最差。结论:熵权系数法可用于评价抗老年痴呆精神类药物的治疗效果。
Objective:To investigated the application of entropy weight coefficient method in clinical treatment effect anti-dementia psychiatric drugs.Methods: selected 167 patients with dementia in our hospital from January 2009 to JUly 201 1 ,Randomly divided into risperidone groups (21 cases), Huperzine groups(25 cases), Donepezi] group (24 cases), olanzapine group (27 cases), olanzapine joint risperidone groups (24 cases), olanzapine joint Huperzine groups(22 cases), olanzapine joint Donepezil group (25 cases),after 8week treatment,we selected MMSE,Behave-AD,ADL as index,then the comprehensive evaluation of three index was carried with entropy method .Results:olanzapine joint risperidone groups could make a best therapy effect and risperidone was worst.Conclusion:The entropy method may become a new approach evaluted the effect of anti-dementia psychiatric drugs synthetically.
出处
《求医问药(下半月刊)》
2012年第7期521-522,共2页
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