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安搏诺与安搏维治疗中老年高血压的疗效比较

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摘要 目的比较安搏诺(厄贝沙坦/氢氯噻嗪)与安搏维(厄贝沙坦)对中老年高血压的治疗效果。方法将64例经基础降压治疗后仍未达标(达标标准<150/90mmHg)的中老年高血压患者随机分为2组,一组加用安搏诺(厄贝沙坦150mg/氢氯噻嗪12.5mg),另一组加用安搏维(厄贝沙坦150mg),两药均每日1次,口服治疗12周,观察血压、心率、血尿酸,血肌酐、血钾、血糖的变化。结果降压总有效率:安搏诺组为87.5%,安搏维组为81.5%;达标率安搏诺组为90.6%,安搏维组为83.3%;两组在治疗12周后相比血压,心率及血钾、血肌酐、血尿酸、血糖等指标较治疗前无明显差异;两药不良反应轻微,未发现明显的不良反应。结论安搏诺与安搏维治疗中老年高血压在疗效、安全性和药物的依从性方面均较好,相比之下安搏诺起效更快,降压有效率、达标率更高。
作者 方瑞娟
出处 《求医问药(下半月刊)》 2012年第7期546-547,共2页 Seek Medical and Ask The Medicine
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