金毛七化学成分研究

Chemical Constituents from Astilbe myriantha

目的:研究金毛七Astilbe myriantha的化学成分。方法:运用柱层析、重结晶等多种分离技术,根据理化性质和波谱数据鉴定化合物的结构。结果:从金毛七95%乙醇提取物中分离得到10个化合物,分别鉴定为:β-谷甾醇(1)、对羟基苯甲酸甲酯(2)、阿魏酸(3)、岩白菜素(4)、没食子酸(5)、(+)-儿茶素(6)、3β-acetoxy-6β-hydroxy-olean-12-en-27-oic acid(7)、3β-hydroxyolean-12-en-27-oic acid(8)、3β,6β-dihydrolean-12-en-27-oic acid(9)和3β-hydroxyurs-12-en-27-oic acid(10)。结论:化合物1～7为首次从该植物中分离得到。

Objective：To study the chemical constituents from Astilbe myriantha.Methods：The constituents were isolated and purified by column chromatography methods and recrystallization.Their structures were identified on the basis of physiochemical properties and special analysis.Results：Ten compounds were isolated from 95% ethanol extract of Astilbe myriantha and their structures were identified as：β-sitosterol（1）,methyl p-hydroxy benzoate（2）,ferulic acid（3）,bergenin（4）,gallic acid（5）,（＋）-catechin（6）,3β-acetoxy-6β-hydroxyolean-12-en-27-oic acid（7）,3β-hydroxyolean-12-en-27-oic acid（8）,3β,6β-dihydrolean-12-en-27-oic acid（9）and 3β-hydroxyurs-12-en-27-oic acid（10）.Conclusion：Compounds 1~7 are isolated from this plant for the first time.