早发型重度子痫前期终止妊娠时机及分娩方式与围生儿结局的关系研究

Timing and Mode of Delivery on Early Onset Severe Preeclampsia Termination of Pregnancy

目的:探讨早发型重度子痫前期终止妊娠时机和分娩方式对围生儿结局的影响。方法:随机抽取在2005年1月～2010年12月这6年时间里,在我院就诊的早发型重度子痫前期的患者中抽取病例200例,将其分为A、B组,平均每组100例。A组患者为<34周终止妊娠的孕妇,B组为≥34周终止妊娠的孕妇。按分娩方式分为两组:阴道分娩组和剖宫产组。对两组的产妇并发症发生率及围生儿结局进行比较分析。结果:研究结果显示,A组孕妇的围生儿病死率都明显高于B组患者,有显著的统计学差异(P<0.05);两组产妇的并发症情况基本相同,没有显著的统计学差异(P>0.05)。结论:对于患有早发型重度子痫的患者来说,将孕周延长至34以上再终止妊娠,其围生儿的结局会比较理想,患者也不会出现特有的并发症现象,值得在今后对该类患者进行治疗的过程中予以使用和推广。

Objective To explore the influence on perinatal outcome of termination and childbirth way on early - onset severe preeciampsia patients. Methods 200 patients undergoing early - onset severe preeclampsia from January 2005 to December 2012 in our hospital were collected stochasticly and analyzed retrospectively First, patients were divided into two groups according to the termination, Group A （n = 100） was patients whose termination were less than 34 gestational weeks, while in group B （ n = 100）, the termination were equal or greater than 34 gestational weeks. And then divided the patients into two groups by childbirth way, one was vaginal delivery group and the other was cesarean section group. Results The results showed that the peri- natal mortality in group A was obviously higher than that in group B, it had statistical significance between two groups （ P 〈 0.05 ）, while the incidence of maternal complications was similar, there was no significant statisti- cal difference （ P 〉 O. 05）. Conclusions For patients of early - onset severe preeclampsia, the perinatal out-come would be ideal if the gestational weeks of termination were greater than 34, and there wont be the unique syndromes. It is useful for to the treatment of these patients in future.