前列腺素E_1治疗老年糖尿病肾病临床观察

A clinic observation of therapeutic effect of prostaglangin E 1 in senile diabetic nephropathy

目的 :探讨前列腺素 E1 对老年糖尿病肾病的疗效。方法 :将 6 8例糖尿病肾病患者随机分为治疗组 (38例 )和对照组 (30例 ) ,治疗组为对照组基础上予前列腺素 E1 90 ug静脉点滴 ,每日一次 ,共用 2 1d。结果 :治疗组早期糖尿病肾病 2 4 h尿白蛋白排泄率和临床期糖尿病肾病 2 4 h尿蛋白定量较治疗前及与对照组相比明显降低。结论 :前列腺素 E1 是治疗老年糖尿病肾病是一种安全、有效的药物。

Objectives:[WT5BZ]To assess the efficacy of prostaglangin E 1 in senile diabetic nephropa.thy.[WT5HZ]Methods:[WT5BZ]68senile diabetic nephropathy patients were randomly assingde to one of two groups,namely A(38)and B(30),ong being treated with prostaglandin E 1 90ug/d.The duration of therapy was 21 days. [WT5HZ]Results:[WT5BZ]24h UAER in early stage diabetic nephropathy and 24h ration of urine albumin in clinic-stage diabetic nephroathy were sinificantly discreased in group A as compared with those before treatment and in group B.[WT5HZ] Conclulsion:[WT5BZ]Prostaglandin E 1is a safe and effective medicament in treatment of diabetic nephropathy. [WT5HZ]