酒石酸布托非诺并丙泊酚对无痛人工流产术的效果

THE EFFECTIVENESS OF BUTORPHANOL COMBINED WITH PROPOFOL IN PAINLESS INDUCED ABORTION

目的了解酒石酸布托非诺联合丙泊酚麻醉用于无痛人工流产的效果。方法拟实施无痛人工流产术病人100例,妊娠囊大小在8周内,随机分为观察组和对照组,各50例。观察组给予丙泊酚配伍酒石酸布托非诺静脉麻醉,对照组给予丙泊酚静脉麻醉,观察并比较两组术中麻醉情况,术中及术后阴道流血量,苏醒后5、15、30min子宫收缩痛的视觉模拟疼痛(VAS)评分。结果对照组术中肢体动例数多于观察组,差异有显著性(χ2=4.557,P<0.05);两组术中和术后阴道流血量比较差异无显著性(t=0.81、1.54,P>0.05);观察组苏醒后5、15、30min VAS评分均明显低于对照组,差异有显著性(t=7.97～9.00,P<0.05)。结论无痛人工流产术中加用酒石酸布托非诺,能增强病人术中的麻醉效果,不影响术中及术后子宫收缩,有效抑制人工流产术后子宫收缩痛。

Objective To observe the efficacy of combined butorphanol-propofol anaesthesia for painless induced abortion.Methods This study consisted of 100 patients scheduled for the abortion,who were evenly randomized to observation group and control group,the size of gestation sacs was within eight weeks.Intravenous anaesthesia was done by using butorphanol combined with propofol for the patients in observation group,and propofol for those in the control group.A comparison was carried out between the two groups in regard to the condition of anesthesia,intraoperative and postoperative vaginal bleeding,and VAS score after analepsia.Results The limb kinetic cases in the control group were more than that in the observation group,being significantly different between the two groups（χ2=4.557,P〈0.05）;no significant difference was noted between the two groups regarding vaginal bleeding（t=0.81,1.54;P〈0.05）;the VAS score in the observation group was lower than that in the control（t=7.97-9.00,P〈0.05）.Conclusion The use of butorphanol besides propofol can enhance the anesthetic effect at surgery,and not influence the uterine contraction during and after operation,which effectively suppresses postoperative pain due to uterine contraction.