脑型多发性硬化的MRI诊断

MRI DIAGNOSIS FOR BRAIN MULTIPLE SCLEROSIS

目的探讨脑型多发性硬化(MS)的MRI特征,以提高其诊断准确性。方法回顾性分析我院诊治的48例脑型MS病人的MRI特征。结果本组48例脑型MS病人MRI表现为病灶多发、大小不一、多数位于侧脑室旁白质区、半卵圆中心和皮质下区,T1WI为低、稍低及等信号,T2WI和FLAIR为不均匀高信号,DWI在急性期为略高信号,慢性期为等或低信号。33例行增强扫描病人18例呈中等或明显强化,5例轻微强化,10例无强化。本组胼胝体信号异常22例,胼胝体萎缩16例,脑萎缩25例。结论多种MRI检查技术综合分析是诊断脑型MS的最佳方法。

Objective To investigate the MRI features of brain multiple sclerosis（BMS）,and raise its accuracy in the diagnosis of this condition.Methods A retrospective analysis was done of MRI features in 48 cases with BMS.Results Of the 48 patients reviewed,the MRI appearance was multiple foci,difference in size,mostly located at periventricular white matter area,centrum semiovale or subcortical area,T1WI was low and appeared as isotonic signal,T2WI and FLAIR were not homogeneous high signal.DWI in acute stage showed a little higher signal,in chronic phase,manifested as isotonic or low signal.An enhanced scan was done in 33 cases,in which,18 showed moderately or obviously enhanced,five slightly enhanced,and 10 with no enhancement.Abnormal signal was observed in corpus callosum in 22 cases,atrophy of corpus callosum was noted in 16,and cerebral atrophy in 25.Conclusion A comprehensive analysis of MRI is the best choice for thr diagnosis of BMS.