栓塞微球联合碘化油在原发性肝癌TACE术中的应用疗效

The Clinical Effect of Application of Embolization Microspheres and Iodized Oil to Treat Primary Liver Cancer with TACE

目的:评价应用栓塞微球及碘化油治疗原发性肝癌的临床疗效及观察栓塞治疗后的不良反应。方法:回顾性分析2009年7月～2011年3月我科21例采用栓塞微球及碘化油栓塞介入治疗原发性肝癌患者资料,按照"WHO实体肿瘤疗效评价"原则进行评价临床疗效及术后不良反应。结果:应用栓塞微球及碘化油介入治疗原发性肝癌后,21例患者中完全缓解2例、部分缓解8例、稳定10例、进展1例。有效率为47.6%,临床获益率为95.2%,且肿瘤平均缩小40%。介入术后21例中发热8例,占38.1%;腹痛伴嗝逆1例,占4.7%;恶心呕吐4例,占19.04%。结论:栓塞微球联合碘化油在原发性肝癌介入治疗中栓塞效果明显,临床疗效确切,不良反应少。

Objective：To evaluate the clinical effect of application of embolization microspheres and iodized oil to treat Primary liver cancer and observe the adverse reactions.Methods：make a retrospective analysis of the data of 21 patients who suffered this cancer and were treated by intervention of embolization microspheres and iodized oil from July in 2009 to March in 2011 and evaluate the effects and adverse reactions according to WHO Evaluation of solid tumors.Results：By the intervention of embolization microspheres and iodized oil to treat Primary liver cancer,2 patients were totally relieved,8 patients were partly relieved,ten were stable and one was improved.The efficiency was 47.6%,clinical benefit rate was 95.2% and the tumor shrink by 40% on average.After the operation 8 cases caught fever covering 38.1%;one case suffered abdominal pain with Belch inverse,covering 4.7%;4 cases suffered Nausea and vomited covering 19.04%.Conclusion：There are obvious effects of embolization by applying this method,its clinical effects are exact and the adverse reactions are few.