84例帕金森病中西医结合治疗的临床效果分析

Clinical Analysis of Integrative Medicine in the Treatment of 84 Patients with Parkinson's Disease

目的:探讨中西医结合治疗在帕金森病患者临床治疗中的应用效果,并与单纯西医药治疗对比,总结工作经验,为今后临床工作提供参考依据。方法:选取2008年4月至2012年1月间于我院门诊及住院部诊断为帕金森病患者84例,随机分为对照组和观察组,每组42人,给予对照组患者单纯西药治疗,在对照组患者治疗基础上给予观察组患者中药配合治疗。结果:观察组治疗有效率85.71%明显高于对照组治疗有效率59.52%,组间差异在统计学上有意义(P<0.05);观察组共出现不良反应5例,不良反应发生率为11.90%,对照组共出现不良反应12例,不良反应发生率为28.57%,两组不良反应发生率间差异比较明显,具有统计学意义(P<0.05);观察组Webster量表评分、PDRS评分均较对照组相应指标低,组间差异均具有统计学意义(P<0.05);观察组平均美多巴每日用量明显低于对照组,组间差异比较明显,在统计学上有意义(P<0.05)。结论:中西医结合治疗是临床上治疗帕金森病的一种安全、有效、经济的治疗手段,其效果较单纯西医治疗更佳。

Objective：To investigate the effect of integrative medicine in the clinical treatment of Parkinson’s disease,compared with western medicine alone treatment,summary of work experience,provide a reference for future clinical work.Methods：the Parkinson’s disease patients 84 cases of hospital outpatient and inpatient department diagnosis were randomly divided into control group and observation group,42 people in each group from April 2008 to January 2012,giving the control group in patients with western medicine alone,give the patients in the control group patients on the basis of with the treatment of Chinese medicine.Results：The observation group treatment efficiency of 85.71% was significantly higher than the control group treatment efficiency of 59.52%,the difference between the groups was statistically significant（P〈0.05）;there were five cases of the observation group adverse reactions,adverse reactions incidence rate of 11.90%,there were 12 cases of the control group adverse reactions,adverse reaction rate was 28.57 percent,the differences between the two groups of adverse events was statistically significant（P〈0.05）;the Webster scale score PDRS score of the observation group were lower than the control group,the difference between the groups were statistically significant（P〈0.05）;the average Madopar daily dosage of the observation group was significantly lower than the control group,the difference between the groups were statistically significant（P 〈0.05）.Conclusion：Integrative Medicine is a safe clinical treatment of Parkinson’s disease,effective treatment of the economy,its effect is better than a simple Western medicine treatment.