新生儿肺液转运机制与调控

Mechanism and regulation of alveolar fluid transport in neonates

肺液转运和新生儿肺发育密切相关，新生儿呼吸系统疾病如湿肺、肺透明膜病、肺炎多与肺液转运减少有关。该文介绍新生儿肺液平衡-肺液分泌与吸收平衡的特点，肺液增多的临床主要因素、重要的肺液转运机制及其调控，雾化吸入8受体激动剂或糖皮质激素是可行的治疗策略。

Alveolar fluid transport is closely associated with neonatal lung development neonatal respiratory diseases, such as wet lung, pulmonary hyaline membrane disease, pneumonia, which are related with decreased lung fluid transport. This review introduces the characteristics of neonatal pulmonary fluid balance,including lung fluid secretion and absorption equilibrium, list clinical factors which can increase pulmonary fluid, explain important lung fluid transport mechanisms and their regulations. Inhaling beta agonists or glucocorticoid is a viable therapeutic strategy.