护理干预在华蟾素治疗恶性肿瘤中的作用

Effects of Nursing Intervention in Cancer Treatment by Cinobufotalin

目的探讨预防或减轻华蟾素治疗恶性肿瘤毒副反应的最佳护理措施。方法 180例接受华蟾素治疗的恶性肿瘤患者随机分为试验组和对照组,每组90例。对照组按照常规输液流程进行护理操作;试验组在常规护理的基础上,进行心理护理、静脉评估、硫酸镁湿敷和局部保温等。结果试验组局部皮肤发红、液体外渗和血管疼痛的发生率均低于对照组,差异有统计学意义(P<0.05)。结论有效的护理干预能够预防或减轻输注华蟾素引起的毒副反应。

ObjecUve To explore the nursing interventions to prevent or relieve the toxicities of anticancer treatment by cinobufotalin. Methods The 180 cancer patients accepted the cinobufotalin treatment were divided into the experimental group and the control group. The 90 patients in the control group accepted routine nursing care; while, besides routine nursing care, the 90 patients in the experimental group accepted nursing interventions, including psychological nursing, vein assessment, wet dressing by magnesium sulphate and local thermal insulation. Results The incidence rate of skin redness, fluid extravasation and blood vessel pain in the experimental group were lower than that in the control group （P 〈 0. 05）. Conclusion Effective nursing interventions can prevent or relieve the toxicities of antieancer treatment by cinobufotalin.