早期动脉粥样硬化与后期血管事件发生的相关分析

Correlation analysis of early atherosclerosis with follow-up vascular events

目的探讨早期动脉粥样硬化患者颈动脉内-中膜厚度（IMT）与后期发生血管事件的相关性。方法采用超声检查对164例早期颈动脉粥样硬化患者颈动脉IMT进行测量，随访10-36个月，平均（26±4）个月，对后期发生的心脑血管事件进行统计分析。结果血管事件总发生率19．5％（32／164），IMT≤1．1lmm组血管事件发生率6．7％（6／89）；IMT〉1．11mm组血管事件发生率34．7％（26／75），为前者的5．04倍；IMT每增加0．1mm，血管事件风险增加1．37倍。结论IMT可以作为独立预测早期CAS患者血管风险的指标。

Objective Through measuring the carotid intima-media thickness （IMT） of the patients with early stage carotid atherosclerosis （CAS） disease, to indicate the subsequent occurrence of vascular events. Methods The carotid IMT of 164 patients with early stage CAS was measured by uhrasonography with （26 ± 4） months follow-up. The data of vascular events were statistically analyzed. Results The overall incidence rate of vascular events was 19.5% （32/164） ; the incidence of the group IMT≤1. 11 mm was 6. 7% （6/89） ; the group IMT 〉 1.11 mm was 34.7% （26/75） ; each additional 0. 1 mm above the IMT ≤ 1.11 mm benchmarks, the risk of vascular events had a 1.37-fold increase. Conclusion IMT can be an independent predictor of vascular events risk in patients of early CAS and provide a clinical basis in the early CAS prevention and treatment.