急性颅脑损伤后继发肺部感染的临床分析

Clinical analysis of lung infection caused by acute craniocerebral trauma

目的探讨急性颅脑损伤后继发肺部感染的原因及预防方法。方法对我院278例急性颅脑损伤患者的临床资料进行回顾性分析。结果格拉斯哥昏迷评分（GCS）≥5分者感染率11．6％（23／198），低于GCS〈5分者感染率E23．7％（19／80）]；气管未切开者感染率为10．6％（24／226），低于气管切开者感染率[25．0％（13／52）]；年龄〈60岁者感染率为9．1％（20／219），低于年龄≥60岁者[28．8％（17／59）]；广谱抗生素使用〈7d者感染率为9．8％（18／183），低于≥7d者感染率[21．1％（20／95）]。以上感染率比较，差异均有统计学意义（均P〈0．05）。结论急性颅脑损伤患者易继发肺部感染，临床应积极预防肺部感染，针对可能造成的感染因素给予相应的治疗措施。

Objective To study the reasons and prevention for lung infection caused by acute craniocerebral trauma. Methods The clinical data of patients with acute craniocerebral trauma in craniocerebral department of our hospital were retrospectively analyzed. Results The infection rate of GCS （ glasgow coma scale） score ≥5 [ 11.6% （23/198）] was lower than the infection rate of GCS score 〈 5 [ 23.7% （19/80） ] ; the rate of nontracheotomy [ 10. 6% （24/226） ] was lower than that of tracheotomy [25.0% （13/52） ] ; the infection rate of age 〈 60 [ 9. 1% （20/219）] was lower than that of age ≥ 60 [ 28.8% （17/59）]; the infection rate of using antibiotic 〈7 d [9. 8% （18/183） 1 was lower than the infection rate of using antibiotic ≥7 d [21.1% （20/95） I ; there were significant differences （ all P 〈 0. 05 ）. Conclusion Patients with acute cranioeerebral trauma would easily have secondary lung infection. It is worthwhile to pay more attention and take appropriate measures to prevent factors of lung infection.