深静脉血栓对重症监护室患者的影响

Influence of deep vein thrombosis on prognosis of critical illness patients in intensive care unit

目的探讨深静脉血栓（DVT）对重症监护室（ICU）重症患者的影响。方法调查2009年1月至2011年1月人住本院ICU超过48h患者的病历资料，病例对照配对研究。比较DVT组患者和（对照组）患者ICU住院时间、机械通气时间及ICU病死率。结果526例患者中有62例（11．79％）患有DVT，与对照组相比，DVT组患者机械通气时间更长[（17±11）d比（13±9）d，P〈0．05]，ICU住院时间更长[（21±15）d比（16±10）d，P〈0．05]，病死率更高[（50．0％（31／62）比34．5％（21／62），P〈0．05]。结论ICU重症患者DVT患病率高，DVT明显延长了ICU重症患者带机时间、ICU住院时间，增加了ICU死亡率。

Objective To evaluate whether the deep vein thrombosis （DVT） influence prognosis of critical illness patients in intensive care unit（ICU）. Methods The case records of patients who stayed more than 48 hours in ICU from Jan 2008 to Jan 2011 were reviewed. The durations of mechanical ventilation, ICU stays and ICU mortality between DVT group and control group were compared. Results Sixty-two patients （ 11.79% ） developed DVT in ICU from Jan 2008 to Jan 2011. Compared with patients without DVT, DVT patients had longer durations of mechanical ventilation[ （ 17 ± 11 ）d vs （ 13 ±9）d, P 〈 0.05 ] , longer ICU stays[ （21 ± 15 ） d vs （ 16 ± 10） d,P 〈 0. 05land higher mortality[ （50.0% （31/62） vs 34.5% （21/62） ,P〈0.05]. Conclusions Patients in ICU have a high incidence of DVT. DVT significantly prolonged the durations of mechanical ventilation and ICU stays and increases the ICU mortality.