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肝硬化腹水伴自发性细菌性腹膜炎的诊断及治疗 被引量:18

Diagnosis and treatment of spontaneous bacterial peritonitis in patients with liver ascites
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摘要 自发性细菌性腹膜炎(spontaneous bacterial peritonitis,SBP)是肝硬化腹水患者的一种常见而严重的并发症,指在无腹腔内邻近器官直接细菌来源(如肠穿孔、肠脓肿)的情况下发生的腹膜急性弥漫性细菌感染,感染主要源于肠道、胆道及泌尿道等,尤其易发生于这些部位存在炎症或梗阻时,血行感染少则^[1]。
作者 吴海清 王晖
出处 《临床肝胆病杂志》 CAS 2012年第9期651-653,共3页 Journal of Clinical Hepatology
基金 国家自然科学基金(No:81070334) 上海市科技发展基金(No:10411966800) 中国肝炎防治基金会王宝恩肝纤维化研究基金
关键词 肝硬化 腹水 腹膜炎 liver cirrhosis ascites peritonitis
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  • 1Koulaouzidis A, Bhat S, Karagiannidis A, et al. Spontaneous bacterial peritonitis [ J ]. Postgrad Mecl J, 2007, 83 ( 980 ) : 379 -383.
  • 2European Association for the Study of the Liver. EASL clinical practice guidelines on the management of ascites, spontane- ous bacterial peritonitis, and hepatorenal syndrome in cirrho- sis[J]. J Hepatol, 2010, 53(3) : 397 -417.
  • 3Mounzer R, Malik SM, Nasr J, et al. Spontaneous bacterial peritonitis before liver transplantation does not affect patient survival[ J ]. Clin Gastroenterol Hepatol, 2010, 8 ( 7 ) ; 623 - 628.
  • 4吴孟超,李孟华.实用肝病学[M].第一版.北京:人民卫生出版社,2011:510-513.
  • 5Runyon BA: AASLD Practice Guidelines Committee. Manage- ment of adult patients with ascites due to cirrhosis: an update [J]. Hepatology, 2009, 49(6) : 2087 -2107.
  • 6冯鑫,闫杰.2010年欧洲肝脏研究协会《肝硬化腹水、自发性细菌性腹膜炎、肝肾综合征临床实践指南》简介[J].胃肠病学和肝病学杂志,2011,20(3):291-294. 被引量:34
  • 7Mostafa MS, El -Seidi EA, Kassem AM, et al. Detection of ascitic fluid infections in patients with liver cirrhosis and asci- tes[J]. Arab J Gastroenterol, 2011, 12(1): 20-24.
  • 8Such J, Frances R, Munoz C, et al. Detection and identifica- tion of bacterial DNA in patients withcirrhosis and culture - negative, nonneutrocytic ascites[ J ]. Hepatology, 2002, 36 (1): 135-141.
  • 9Frances R, Benlloch S, Zapater P, et al. A sequentialstudy of serum bacterial DNA in patients with advanced cirrhosis and ascites [ J ]. Hepatology, 2004, 39 ( 2 ) : 484 -491.
  • 10Such J, Hillebrand D J, Guarner C, et al. Tumor necrosis fac- tor e, interleukin -6, and nitric oxide in sterile ascitic fluid and serum from patients with cirrhosis who subsequently de- velop ascitic fluid infection[J]. Dig Dis Sci, 2001, 46( 11 ) :2360 - 2366.

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