中药艾灸改善腹膜透析患者营养不良的临床研究

Effects of Moxibustion on Peritoneal Dialysis Malnutrition in Hyper-Transport CAPD Patients

目的:观察中药艾灸对高腹膜转运CAPD患者腹膜营养不良的影响。方法:高腹膜转运CAPD患者26例随机分为两组,治疗组(中药艾灸)与对照组各13例,观察治疗前后透析超滤量(UF)、C反应蛋白(hs-CRP)、白细胞介素6(IL-6)、血清白蛋白(Alb)、前白蛋白(Pre-A)及中医症状计分和改良定量主观整体评估法(MQSGA)评分的变化。结果:治疗组治疗后24h总超滤量明显增加,hs-CRP、IL-6明显下降,Alb及Pre-A明显增加,中医症状计分和MQSGA评分增加,优于对照组(P<0.05)。结论:中药艾灸可以有效提高透析超滤量,减轻高腹膜转运CAPD患者的微炎症状态,改善营养不良。

Objective：To investigate effects of moxibustion on peritoneal dialysis Malnutrition in hyper - transport continu- ous ambulatory peritoneal dialysis （CAPD） patients. Methods ：26 cases of hyper -transport CAPD patients were randomly divided in- to two groups： 13 cases of treatment group （with moxibustion） and 13 cases of control group （no moxibustion）. The ultrafiltration （UF） amount, serum high - sensitivity C - reactive protein （ hs - CRP）, interleukin - 6 （ IL - 6 ）, serum albumin （ A1b）, serum Pre - albumin（ Pre -A）, the score of chinese medical symptom and modified quantitative subjective global assessment of nutrition（MQSGA） were be contrasted after treatment. Results： After using moxibustion, the total amount of 24 - hours ultrafiltration significantly in- crease, the concentration of hs - CRP and IL - 6 significantly decrease （ P 〈 0.05 ）, the concentration of Alb and Pre - A significantly increase（P 〈0.05）, the rating of chinese medical symptom and MQSGA also significantly increase（ P 〈 0.05 ）. Conclusion： The moxibustion effectively increases the amount of uhrafiltration, reduce the microinfiammation and improve malnutrition in hyper - trans- port CAPD patients.