2010年天津市河北区部分人群乙型肝炎病毒血清学调查

Seroepidemiological Survey on Hepatitis B Virus Among Population in Hebei District,Tianjin City,2010

[目的]了解人群乙肝病毒感染/免疫状况,评价实施乙肝疫苗接种措施的效果。[方法]2010年,在天津市河北区采用多阶段抽样方法,抽取4个调查点,对178名1～59岁常住人口进行血清乙肝病毒感染指标检测。[结果]检测178人,HBsAg阳性率为1.12%,抗-HBs阳性率为52.25%,抗-HBc阳性率为10.11%,HBV感染率为10.11%。上述4项指标,男性与女性的差异均无统计学意义(P>0.05);抗-HBs阳性率,有随着年龄的升高而下降的趋势(P<0.01),抗-HBc阳性率和HBV感染率,均为≥30岁高于<30岁(P<0.05)。有乙肝疫苗免疫史者与无免疫史者比较,抗-HBs阳性率前者高于后者(P<0.01),HBsAg阳性率、抗-HBc阳性率、HBV感染率,2组的差异均无统计学意义(P>0.05)。[结论]河北区一般人群HBV感染率较低。

[Objective]To understand the hepatitis B infection and immunization status among population,so as to eval- uate the immunizing effect of hepatitis B vaccination. [Methods]A multi-stage sampling method was used to carry out sero logical survey for 178 resident subjects aged from 1 to 59 in Hebei district,2010. [Results]For the surveyed population,the seroprevalence of HbsAg,anti-HBs,and anti HBc was 1.12 %, 52.25 %, and 10. 11 %, and had no statistical difference be- tween the male and female（ P 〉0.05） ;compared with the 1-14 years group and 15 59 years group, the seroprevalence of anti-HBs was significantly higher in the 1-14 years age group（ P〈0.01） ,and the two age groups had no difference in se- roprevalence of HbsAg, and anti-HBc（ P 〉0.05）. [Conclusion]The infection prevalence is lower among population in He- bei district.