C反应蛋白血尿酸与2型糖尿患者工胰岛素泵使用的关系

The relationship between C-reactive protein plasma uric and diabetic macroangiopathy

目的了解人工胰岛素泵强化治疗(CSII)对2型糖尿病合并大血管病变患者C反应蛋白和血尿酸的关系。方法将32例合并大血管病变T2dM患者,随机分为两组,分别使用人工胰岛素泵强化治疗和使用诺和灵30R(笔式预混胰岛素)治疗后,观察并比较血尿酸和CRP变化特点。结果胰岛素泵强化组的BMI、FBG、TG、LDL-C、SBP及Hs-CRP均明显低于对照组(使用诺和灵30R组),胰岛素泵强化组C反应蛋白及血尿酸明显低于对照组。结论 CSII有助于迅速降低C-反应蛋白和血尿酸水平,迅速减轻患者体内炎性反应,从而进一步降低大血管病变风险。

Objective To artificial CSII intensie treatment for type 2 diabetes combined with vascular disease C-reactive protein and plasma uric type 2 diabetes serious harm human health life. Methods Random- ly divided the 32 cases with macroangiopathy T2 dM patients into two groups, namely using artificial intensie treatment and use the insulin pump＇s spirit and 30 R （pen type blends insulin） after treatment, Observing and comparing the CRP change features plasma uric. Results Insulin pump strengthen group BMI, FBG, TG, LDL-C, SBP and Hs-CRP were significantly lower than those of the control group （use＇s Nohelin 30 R group）, insulin pump strengthen group C-reactive protein and blood uric acid was significantly lower than the control group. Conclusion CSII help rapidly reduces the C-c-reactive protein and blood uric acid levels, quickly re- duce the patients＇ bodies inflammatory reaction, so as to further reduce the risk of vascular lesions.