重度子痫前期围生儿206例结局分析

Outcome analysis of 206 preinatals with severe preeclampsia

目的:探讨重度子痫前期(PE)终止妊娠时机对围生儿结局的影响。方法:对206例重度PE围生儿结局情况进行回顾分析,包括一般资料、并发症、临床监测指标等。结果:重度PE早发型并发症发生率为93.02%,高于迟发型的83.33%(P<0.05);早发型重症PE新生儿Apgar评分>7分和体重>1 500 g者均低于迟发型(P<0.05和P<0.01),而2种类型的围生儿死亡率分别为18.60%和3.33%,差异有统计学意义(P<0.01)。结论:保守治疗延长孕龄达≥32周可改善围生儿结局;各种监测方法是重度PE保守治疗的前提;终止妊娠时机决定围生儿结局。

Objective：To explore the effects of termination time on perinatals with severe preeclampsia（PE）. Methods：The clinical data,complications and clinical monitoring index of 206 perinatals with evere PE were retrospectively analysed. Results：The incidences of complications of early-onset PE were 93.02%,which were higher than that of late-onset PE（83.33%）（P〈0.05）.The early-onset PE with Apgar score greater than 7 and weight larger than 1500g were lower than that of late-onset PE（P〈0.05 and P〈0.01）.The perinatal mortality rates of two types of were 18.60% and 3.33% respectively,which difference was statistically significant（P〈0.01）. Conclusions：Conservative treatment to extend gestational age for 32 weeks can improve perinatal outcome.Various monitoring methods are the premise of conservative treatment and the termination time can affect the perinatal outcome.