小柴胡汤合升降散治疗慢性咳嗽32例

Xiaochaihu Decoction combined Lifting Powder Treatment of Chronic Cough in 32 cases

[目的]研究小柴胡汤合升降散治疗慢性咳嗽的临床疗效。[方法]根据《咳嗽的诊断与治疗指南(2009版)》的诊断标准,选择慢性咳嗽患者64例随机进入临床研究,其中治疗组、对照组各32例。治疗组用小柴胡汤合升降散治疗,对照组用镇咳宁治疗。两组疗程均为1周,连续治疗观察2个疗程。研究观察主要指标为临床疗效总有效率、治愈率及咳嗽减轻或消失时间。[结果]治疗组总有效率、治愈率分别为87.5%、53.13%,高于对照组的65.62%、28.12%,(P<0.05);治疗组咳嗽开始减轻时间约为5.04±1.57d、咳嗽消失而痊愈的时间为8.14±1.53d,明显优于对照组的6.76±1.70d、9.23±1.81d,(P<0.05)。[结论]慢性咳嗽的中医基本病因病机为"枢机不利,肺气上逆",小柴胡汤合升降散治疗可取得较好的临床疗效。

[ Objective ] To study the clinical curative effect of the Xiaochaihu decoction combined Lifting powder in treating chronic cough. [ Method] According to the＂ cough diagnosis and treatment guide （ 2009 E- dition ）＂ diagnostic criteria, 64 patients with chronic cough were selected in randomly and divided into the treatment group （32 cases） and control group 32 cases. The patients in the treatment group treated with the Xiaochaihu decoction combined Lifting powder while the control group treated with the Zhenkening. The peri- od of treatment in the two groups was 1 weeks, and the continuous treatment observation was 2 weeks. The main indexes for research was the total effective rate, the cure rate and the reduce time or the fade time of cough. [ Result ] The total effective rate and the cure rate in the treatment group was respectively 87.5 % and 53.13% ,while, the control group is respectively 65.62% and 28.12% （P 〈0.05）. The relief times of cough in the treatment group was 5.04 ＋ 1.57 days and the healing times of cough was 8.14 ＋ 1.53days, significant- ly better than those in the control group of 6.76 ＋ 1.70days, 9.23 ＋ 1.81days （P 〈0.05）. [ Conclusion] The basic etiology of chronic cough is the helm adverse while the gas of lung inverse, therefore, a better clini- cal effect can be obtained in chronic cough treated with the Xiaochaihu Decoction combined Lifting Powder.